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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinopathy of prematurity (ROP)
ncRNA name VEGFA shRNA
ncRNA Category shRNA
Disease name retinopathy of prematurity (ROP)
Species Rattus norvegicus
Tissues/Cell_line retinas
Methods shRNA knockdown, fluorescence microscope, phosphohistone labeling
Expression pattern associated
Functional description Targeted treatment with lentivector-driven VEGFA.shRNA permitted physiologic vascularization of the vascular plexi and restored normal orientation of dividing vascular cells.
PubMed ID 24425858
Year 2014
Title Quantitative analyses of retinal vascular area and density after different methods to reduce VEGF in a rat model of retinopathy of prematurity.
Drug-related ncRNA NA

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